In healthy people, the heart can also increase in size. Muscle cells increase their number, and myofibrils accumulate. In both cases, it takes more hard effort to treat. Either the valve through which the heart has to push blood contracts or the valves are not completely closed in this condition. It occurs in response to increased load from a certain organ (e.g. Pathological Hypertrophy: Even after the demand is reduced the tissues do not return to their initial state.ĭepending on the reason that cause it the hypertrophy can be: Physiological Hypertrophy: After the demand is reduced the tissues return to their initial state. Hypertrophy is Divided into Two Types, They are: It occurs in permanent cells (non-dividing, like muscle skeletal, cardiac muscle, etc.). Hypertrophy is only due to the enlargement of the cells of the tissue or organ. It does not include an increase due to adhesion or deposition of fat, or because of cell proliferation. Hypertrophy is the growth of a given tissue or organ. In this article hypertrophy, hyperplasia, and its differences are discussed in detail. It includes hyperplasia, hypertrophy, atrophy, and metaplasia and may be physiological or pathological, depending on whether the stimulus is normal or abnormal.Ī cell may adapt to a certain point, but if the stimulus continues beyond that point, it may result in cell failure, and hence organ failure. Some diseases represent random changes in a cell's ability to proliferate and function normally, and in other situations, the disease occurs when external stimuli cause changes in the cell's environment that prevent the cell from maintaining Homeostasis. Disease happens for a variety of reasons.
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